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Senior Software Developer / Bioinformatician (Genome Annotation and Analysis) | Software Developer1

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Senior Software Developer / Bioinformatician (Genome Annotation and Analysis)

Location:
Colney
Description:

Applications are invited for a Senior Software Developer/Bioinformatician to join the Laboratory of Dr Swarbreck in the Research Faculty of the Earlham Institute, based in Norwich, UK. The role: Global initiatives such as the Earth Biogenome project are contributing to a rapid increase in genomic resources. Annotation of genes and regulatory regions in eukaryotic genomes remains challenging, even within large global initiatives such as the Earth Biogenome the quality of genome annotation will not be uniform, with variation both across and within taxonomic clades. This post will focus on developing novel computational tools and pipelines for large scale annotation and analysis of genes and other genomic features across a diverse range of species including plants, mammals, fish and protists. A key focus will be continuing the development of REAT - EI's Robust and Extendable eukaryotic Annotation Toolkit , building new workflows to consolidate, validate, and resolve differences in gene annotations across clades, subspecies, and haplotypes. The role will develop scalable and robust methods to annotate eukaryotic species with large, repeat rich and polyploid genomes, utilising data from cutting edge sequencing technologies including Pac Bio Iso Seq and Nanopore. As part of the Core Bioinformatics Group you will: • Design and develop accurate and scalable computational pipelines for the annotation and analysis of complex eukaryotic genomes • Continue development of existing pipelines / annotation tools • Develop tools to support pan-genome analysis and annotation of alternative haplotypes • Develop approaches for integrating data from a variety of sequencing technologies • With the core bioinformatics team produce high-quality, evidence-based genome annotation of protein-coding, lnc RNA and pseudogenes• Utilise modern workflow management and containerisation systems to automate complex workflows. • Keep up to date with modern software engineering. Visit ListedBuy for more information.
Company:
Earlham Institute
Posted:
May 14 on ListedBuy
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